Anti-CCR8 Antibody

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CCR8

Applications

WB, IHC-P, ELISA

Reactivity

Mouse

Formulation

Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Goat

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

ELISA: 1:100,000, IHC-P: 1:400, WB: 1:1,000

Protein Length

27

Secvență

PNVTMTDYYPDFFTAPCDAEFLLRGSM

Imunogen

Synthetic peptide sequence PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to amino acids 7-33 of mouse CDw198.

Aminoacizi

aa 7 - 33

Specificitate

This antibody recognises mouse CDw198, otherwise known as CCR8 (C-C chemokine receptor type 8), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis.CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.

Storage

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului