Anti-CCR2 Antibody

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

CCR2

Applications

WB, IHC-P, ELISA

Reactivity

Human

Formulation

Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide.

Conjugate

Unconjugated

Host

Goat

Clonality

Polyclonal

Product form

Liquid

Concentration

1 mg/ml

Isotype

IgG

Recommended dilutions

ELISA: 1:30,000, IHC-P: 1:100, WB: 1:500

Protein Length

23

Secvență

C-GEEVTTFFDYDYGAPCHKFDVKQ

Imunogen

Synthetic peptide sequence C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminus of human CD192.

Aminoacizi

aa 17 - 39

Specificitate

This antibody recognises an epitope within the N-terminal region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4.Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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