Anti-Calcitonin Receptor / CT-R Antibody

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

Calcitonin Receptor / CT-R

Applications

WB, ICC, IHC-Fr, ELISA

Reactivity

Rat, Mouse

Formulation

Supplied in 10 mM Sodium Phosphate with 0.01% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Polyclonal

Product form

Lyophilized

Concentration

1 mg/ml after reconstitution.

Isotype

IgG

Recommended dilutions

ELISA: 1:20,000, ICC: 1:1,000, IHC-Fr: 1:1,000 - 1:5,000

Reconstitution

Reconstitute with 100 µl of distilled water.

Imunogen

Synthetic peptide corresponding to a region within the C-terminus of rat calcitonin receptor.

Specificitate

This antibody recognises rat calcitonin receptor, also known as CT-R or C1A/C1B.Calcitonin receptor is a seven-transmembrane domain G protein-coupled receptor that binds the protein hormone calcitonin. It is expressed in kidneys, central and peripheral nervous system, skeletal muscle stem cells and osteocytes. Investigations on calcitonin receptor’s function have mainly focused on its role in regulating calcium homeostasis and osteoclast-mediated bone resorption. However, a growing body of evidence suggests that calcitonin receptor could also be involved in foetal morphogenesis and cancer development.Rabbit anti rat calcitonin receptor antibody binds to an intracellular epitope of the calcitonin receptor that is shared by both C1a and C1b rat calcitonin receptor isoforms. It has been shown to cross-react with mouse calcitonin receptor.

Storage

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului