Anti-c-Myc Antibody [MYC/7854R]

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Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

c-Myc

Applications

WB, IHC-P

Reactivity

Human

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Rabbit

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG

Recommended dilutions

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Molecular weight

62-64 kDa

Light chain

kappa

Clonă

MYC/7854R

Imunogen

Recombinant fragment (around Amino Acids 1-200) of human MYC protein. The exact sequence is proprietary.

Specificitate

It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

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