Anti-BRG1 Antibody [5B7]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

BRG1

Applications

IF, WB

Reactivity

Human, Mouse, Monkey

Formulation

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Conjugate

Unconjugated

Host

Rat

Clonality

Monoclonal

Product form

Liquid

Concentration

1 mg/ml

Purification

Protein G affinity chromatography of tissue culture supernatant.

Isotype

IgG2a

Recommended dilutions

IF: 2 µg/ml - 10 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Protein Length

83

Clonă

5B7

Secvență

MQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAP

Imunogen

A recombinant protein corresponding to amino acids 213-295 of human SMARCA4.

Aminoacizi

aa 213 - 295

Specificitate

This antibody recognises special AT-rich sequence-binding protein 2, also known as transcription activator BRG1.SMARCA4 is a member of the SWI/SNF family of proteins. SWI/SNF proteins display ATPase and helicase activities and regulate gene transcription via chromatin remodelling. SMRCA4 is important for spermatogenesis and embryo development. SMARCA4 is also the most frequently mutated chromatin remodeling ATPase in cancer. Mutations in the SMARCA4 have been observed in many tumor subtypes including pancreatic cancers and some types of leukemia. Rat anti Human SMARCA4 antibody detects a band of 180 kDa.

Storage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Documentație

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