Anti-BMI1 Antibody [BMI1/2823]

Pe scurt

Descriere

Specificații

Brand

Antibodies

Mărime

100µg

Țintă

BMI1

Applications

WB, IF, IHC-P

Reactivity

Human, Mouse

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conjugate

Unconjugated

Host

Mouse

Clonality

Monoclonal

Product form

Liquid

Concentration

200 µg/ml

Purification

Protein A/G chromatography.

Isotype

IgG1

Recommended dilutions

WB: 1-2 µg/ml, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Molecular weight

41 kDa

Light chain

kappa

Clonă

BMI1/2823

Imunogen

Recombinant fragment, around amino acids 142-326, of human BMI1 protein. The exact sequence is proprietary.

Specificitate

The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Documentație

• Fișă tehnică (PDF)se deschide pe site-ul producătorului