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PKC-theta inhibitor 1 is the PKCθ inhibitor with an Ki value of 6 nM, inhibits IL-2 production in vivo with an IC50 of 0.19 μM. PKC-theta inhibitor 1 demonstrates a reduction of symptoms in a mouse model of multiple sclerosis.
- COVID-19-immunoregulation
- 1160501-81-4
- C17H15F3N4O
- MedChemExpress
- 348.32
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