Nu există produse adăugate.
JB170
Cod: HY-141512
Concentratie:
98.4%
Per ambalaj
Cantitate
Preţ
Subtotal
10 mg
5.384,72 Lei
0 Lei
100 mg
23.498,16 Lei
0 Lei
25 mg
10.236,89 Lei
0 Lei
10 mM * 1 mL
5.693,73 Lei
0 Lei
50 mg
15.733,38 Lei
0 Lei
5 mg
3.313,67 Lei
0 Lei
Total
0 Lei
Timp de livrare: 1-2 saptamani
Preturile includ TVA 19%
JB170 is a potent and highly specific PROTAC-mediated AURORA-A (Aurora Kinase) degrader (DC50=28 nM) by linking Alisertib, to the Cereblon-binding molecule Thalidomide. JB170 preferentially binds AURORA-A (EC50=193 nM) over AURORA-B (EC50=1.4 µM). JB170-mediated S-phase arrest is caused specifically by AURORA-A depletion. JB170 has excellent ability to inhibit non-catalytic function of AURORA-A kinase.
- Cancer-Kinase/protease
- 2705844-82-0
- C48H44ClFN8O11
- 98.4%
- MedChemExpress
- 963.36
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