# TMRE

**Cod produs:** A270329 · **Brand:** Antibodies · **Categorie:** Assistive Reagents

TMRE este un produs din categoria Assistive Reagents, marca Antibodies, cod A270329. Se livrează în mărimea 25mg, la prețul de 1.996,50 lei cu TVA. Produse destinate exclusiv cercetării. Nu se utilizează în diagnostic sau tratament.

## Specificații

| Caracteristică | Valoare |
| --- | --- |
| Product form | Dark colored solid. |
| Molecular weight | 514.96 Da |
| Purity | 95% (by 1H NMR and HPLC-MS). |
| Solubility | Good in DMF and DMSO. |
| Storage | Shipped at room temperature. Upon delivery, store in the dark at -20°C. Avoid prolonged exposure to light. Desiccate. |
| Cas number | 115532-52-0 |
| Formulă moleculară | C26H27N2ClO7 |

## Mărimi și prețuri

| Mărime | Cod și preț (RON, TVA inclus) |
| --- | --- |
| 25mg | A270329-25 · 1.996,50 lei |

## Descriere

Tetramethylrhodamine ethyl ester perchlorate (TMRE) is widely used for labeling mitochondria in live cells but is not compatible with fixation. This lipophilic and positively charged dye rapidly permeates plasma membranes without interacting with membrane proteins and forming aggregates. TMRE selectively accumulates in active mitochondria due to their transmembrane potential. In addition to staining mitochondria for imaging purposes, TMRE is used for quantitative measurements of mitochondria membrane potential using the Nernst equation. The dye serves as a tool to study mitochondrial function changes and cell viability in response to stimuli or pharmaceuticals of interest. Mitochondrial depolarization caused by apoptosis, necrosis or other factors is characterized by decreased membrane potential and is indicated with decreased fluorescence compared to intact cells that have polarized mitochondria. TMRE applications include fluorescent microscopy, flow cytometry, microplate assays. The dye has an excitation maximum at 549 nm: it can be effectively excited by the blue (488 nm) or yellow-green (561 nm) lasers. Emission of the dye can be detected in the PE channel (maximum at 574 nm).

## Documentație

- [Fișă tehnică (PDF)](https://www.antibodies.com/datasheets/270/A270329.pdf)

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Sursă: https://reactivi.ro/produs/tmre/ · actualizat 9 septembrie 2026